ROCK1 and pulmonary fibrosis: They used a NOTCH1 inhibitor in a mouse model of pulmonary fibrosis, which successfully inhibited the PDGFRβ/Rho associated coiled-coil containing protein kinase 1 (ROCK1) pathway, inhibited the proliferation and differentiation of pericytes, and reduced the severity of fibrosis (Wang et al., 2019).