Indeed, angiotensin receptor blockers (ARBs) and angiotensin converting enzyme inhibitors (ACEi) showed beneficial effects in both PTSD and severe COVID-19, suggesting that dysfunctional RAS may play an essential role in both conditions (Khoury et al., 2012; Marvar et al., 2014; Vian et al., 2017). The gene discussed is ACE; the disease is post-traumatic stress disorder.