The SARS-CoV-2 virus may target BDR4 as it regulates antiviral immunity, including the interferon-gamma (IFN-gamma), a molecule previously associated with both PTSD and affective disorders (Bruenig et al., 2018; Gibbons et al., 2019; Huang et al., 2021). Here, IFNG is linked to post-traumatic stress disorder.