Recently, the CARP RD2RD2 (ptlhthnrrrrrptlhthnrrrrr; +10.4 charge) was investigated as a potential therapeutic candidate for amyotrophic lateral sclerosis (ALS) in a mouse model of mutant superoxide dismutase 1 (SOD1) expression (Post et al., 2021). This evidence concerns the gene SOD1 and amyotrophic lateral sclerosis.