ATP7A and Prader-Willi syndrome: Expression profiling in this study revealed transcripts that may affect early development in PWS, including genes involved in secretory granule regulation (SNTB2 and ATP7A), mTOR signaling (AKT1S1), and peroxisome biogenesis (PEX10), all of which have been implicated in phenotypes of neurodevelopmental disorders (Niciu et al., 2006; Wang et al., 2017; Barone et al., 2019).