For treated hypertensive group, the predictive model for non-dippers was 7 - (0.081 x average office DBP) + (1.474 x dyslipidemia) - (0.297 x serum uric acid) + (1.031 x use of calcium channel blockers) - (0.986 x use of angiotensin-converting enzyme inhibitors) + (0.746 x male gender). The gene discussed is ACE; the disease is metabolic syndrome.