To test this hypothesis, we first showed that overexpression of PRMT1 promoted cell proliferation in MCF7 breast cancer cells by CCK-8 assays (Fig. 1A, B), whereas knockdown of PRMT1 inhibited cell proliferation in MCF7 and MDA-MB-231 breast cancer cells (Fig. 1C–F). Here, PRMT1 is linked to breast carcinoma.