Chronic inflammation fosters consistent acquisition of mutations and epigenetic variations (3) that induce genetic alterations in cells that trigger transcriptional activity of various proteins like NF-κB (4, 5), signal transducer and activator of transcription 3 (STAT3), and hypoxia-inducible factor 1α (6, 7) in tumor cells. Here, NFKB1 is linked to neoplasm.