Recently, Zhang et al. [17] reported that Apo-B had a causal effect on COVID-19 susceptibility (OR, 1.18; 95% CI, 1.07–1.29; P = 0.001) using GWAS data of the Apo-B trait for 24,925 participants of European ancestry and UKBB data with 1221 COVID-19 cases and 4117 controls. Here, APOB is linked to COVID-19.