The frequencies of CD8+ T cells (CD45+ CD3+ CD11b- CD4- CD8+) and Foxp3-CD4+ T cells (CD45+ CD3+ CD11b- CD4+ CD8- Foxp3-) in CT-26 tumor tissues were significantly higher than those in Colon 26 tumor tissues (Fig. 2E and F). Here, FOXP3 is linked to neoplasm.