STAT5A and myeloid neoplasm: In order to supply more evidence to prove that the Dnmt3a is downregulated by Stat5a, the expression levels of p-STAT5a and DNMT3a proteins in other human or murine myeloid tumor cell lines were examined, as shown in Fig. 2A (Supplementary Fig. 5) and Fig. 2B (Supplementary Fig. 6).