SOX2 and posterior cortical atrophy: More importantly, de novo motif analysis of LNCaP-derived cell lines demonstrated that R273C-p53 had the ability to drive wt-p53 to RXR, NFAT, and Sox2 motifs (Supplementary Fig. 4D), which were not observed in control or R273H-p53 expressing lines, with clinical implications for PCa.