PACC1 and infection: The TLR cassette consists of a for our purposes optimized version of mKO2_G67D, termed mKO2_mut, which is joined via T2A site to either puromycin N-acetyl-transferase (PAC) or hygromycin-B-phosphotransferase (HPH), allowing for selection of bulk populations transduced at low multiplicity of infection (MOI).