There was a statistically significant difference between the basal blood glucose and insulin levels at T0 and at T2 (p = 0.0405 and p < 0.0001 respectively); this is in accordance with the literature: Pasanisi et al. conducted a randomized controlled trial evaluating the adhesion to MD and the IGF-1 levels and other markers of insulin resistance in BRCA mutation carriers. This evidence concerns the gene INS and Insulin resistance.