Another point of relevance to miR-34a regulation of NPC differentiation is its role as a TS in brain cancers like glioma and medulloblastoma [113,114] and also in NB via the targeting of multiple oncogenes such as BCL2, MET, c-MYC, MYCN, CDK4, c-SRC and PD-L1 [35,36,37,90,91,92]. Here, MYCN is linked to neuroblastoma.