Furthermore, the ingenuity pathway analysis indicated by inference that the dysregulation of three upstream regulators, MLXIPL, MYCN, and RICTOR, may explain the differences that were observed in the expression of several of the ribosomal proteins between MPN-DLBCL and R-DLBCL specimens (Table 4C, Figure S3). The gene discussed is MYCN; the disease is myeloproliferative disorder.