Similarly, a correlation between the tumour response to atezolizumab and the transcriptional signature of eight genes (IFNG, CXCL9, CD8A, GZMA, GZMB, CXCL10, PRF1 and TBX21) representing interferon signalling, and the presence of CD8+ effector T cells, namely the tGE8, was reported within the ABACUS neoadjuvant study [39]. This evidence concerns the gene CD8A and neoplasm.