FCGR3A and colorectal carcinoma: While we did not determine the cellular source, it is known that these cytokines can be produced by a variety of cells [39,40], including activated NK cells [49,50], and, perhaps more likely in our experiments, CD16+ monocytes and macrophages that constituted the second most frequent population of CD16+ cells in patient PBMC and the dominant fraction in the patient peritoneal CRC metastases [42,51,52].