To further confirm that the bispecific C-7 VHH-mediated tumor control that was observed in co-cultures of dissociated CRC samples and autologous PBMC was mediated predominantly by CD16+ NK cells, we assessed the distribution of CD16 expressing immune cell subsets present in PBMC of patients with peritoneal CRC metastasis. The gene discussed is FCGR3B; the disease is neoplasm.