In the latest WHO classification of sarcomas, it is not only the Ewing’s sarcomas that have been reclassified on the basis of genomic characteristics, and new types of epithelioid hemangioendothelioma are described based on rearrangements (WWTR-CAMTA1 and YAP1-TFE3). This evidence concerns the gene YAP1 and epithelioid hemangioendothelioma.