CML cells express both leukemia-specific antigen derived from the BCR-ABL fusion protein and leukemia-associated antigens, including Wilms tumor 1(WT1), proteinase 3 (PR1), and preferentially expressed antigen of melanoma (PRAME) [87,88,89,90]. This evidence concerns the gene BCR and chronic myelogenous leukemia, BCR-ABL1 positive.