On the other hand, the diagnostic role and usefulness of NT-proBNP as a screening tool for heart valves involvement in the context of carcinoid syndrome and as a predictor for lung cancer surgery related atrial fibrillation seem to be well established [4,5,6], as well as the prognostic role and the usefulness in monitoring cardiac amyloidosis course of the previously mentioned biomarker together with highly sensitive troponin T (hs-TnT) [7]. This evidence concerns the gene NPPB and carcinoid syndrome.