We did not observe differences in innate inflammatory immune biomarkers including IL8, TNFα and sTNFRII, consistent with a previous study that examined these factors in 22 pairs of smoking-discordant twins [10] (other soluble markers associated with HL, FL and microbial translocation examined in our study were not examined in this previous twin study). The gene discussed is TNF; the disease is Hodgkins lymphoma.