Among others, the successful fusion and formation of various structures made of silk was described for (i) F3 peptide, which binds specifically to nucleoin expressed on the surface of angiogenic endothelial and some tumor cells, (ii) CGKRK peptide, which binds to heparan sulfate in tumor vessels, and (iii) Lyp1 peptide, which targets the lymphatic vessels of certain tumors [84,85]. Here, PTPN22 is linked to neoplasm.