CD8A and cancer: Interestingly, we observed that IL-10-producing CD8+ T cells (Figure 5B) were mostly TEMRA and TNAIVE-LIKE cell subsets, except for the eBL children who had significantly more TNAIVE-LIKE cells compared to the Nandi children and adults (p = 0.0005 and p = 0.001, respectively) suggesting an immature EBNA1-specific T cell signature for children with this EBV-associated cancer.