YAP1 and cancer: We analysed the prognostic significance of core Hippo Signalling pathway genes, determined from existing literature [34,35,36], among TCGA cancers, visualised as a heatmap of log10(HR) in Figure 7A. LGG was the only cancer where key Hippo Signalling pathway genes were significant prognostic markers, which further substantiated the rationale for investigating the interaction between TP53 and YAP1 post-chemotherapy.