Hence, our findings indicate that codon 273 mutant tumours are possibly more chemosensitive than TP53 WT and ‘other’ TP53 mutant groups, although, within the ‘other’ mutant group, there may be a number of less frequently occurring mutations that give the same prognostic effect as codon 273, ultimately leading to the TP53 other group trending toward an improved clinical outcome. The gene discussed is TP53; the disease is neoplasm.