TP53 and astrocytoma (excluding glioblastoma): To investigate the distribution of Hippo Signalling pathway gene mRNA expression among TP53 mutants and TP53 WT astrocytoma, we generated a heatmap to visualise TCGA astrocytoma samples in Figure 7B. Clearly, the TP53 WT astrocytoma group showed the highest expression of Hippo Signalling pathway genes.