CXCL8 and carcinoma: Figure 6B provides an example of ChIP-seq, ATAC-seq, and RNA-seq data derived from human epithelial carcinoma cells which were combined to reveal four regions of strong IL-1α-inducible p65 binding (three of which contain a predicted NF-κB motif) to the inducible enhancers and promoters of the prototypical NF-κB target gene CXCL8 (IL8) [62,65].