AKT1 and gastric cancer: In gastric cancer (GC), LINC00511 was highly expressed and further studies found LINC00511 to recruit EZH2 (enhancer of zeste 2 polycomb repressive complex 2 subunit) to the PTEN (phosphatase and tensin homolog) promoter, facilitating its methylation, and subsequently activating the PI3K/AKT pathway, promoting GC cell proliferation, migration, and stemness, while inhibiting GC cell apoptosis [32].