Closer inspection of TCGA PanCancer Atlas cohorts revealed that, although amplification at the HRAS locus is surprisingly rare, SCCs express significantly higher levels of HRAS than adenocarcinomas, and HRAS mRNA is overexpressed in around 30%, 25%, and 10% of cases of HNSCC, UC, and LSCC, respectively (Figure 1). The gene discussed is HRAS; the disease is head and neck squamous cell carcinoma.