With regard to the breast cancer phenotype, 111 (52.9%) trials enrolled patients with various phenotypes, 40 (19.0%) were dedicated to hormone-receptor-positive disease alone, 33 (15.7%) to HER2-positive disease (regardless of hormone receptors), and seven trials (3.3%) to triple-negative breast cancer. The gene discussed is NR4A1; the disease is breast carcinoma.