MITF and melanoma: Bipartite and unipartite network projections of the 19 core microRNAs with the highest degree centrality identified three distinct network hubs, which broadly corresponded to the differentially expressed microRNAs in the ‘keratin’, ‘MITF-low’ and ‘immune’ transcriptomic-subsets previously described in the TCGA melanoma dataset (Figure 1a,b) [27].