In addition, the malignant risk is higher and the cancer progresses faster in the Brg1 (3/7 at 9 w) knockout model than in the Arid1a knockout model (3/15 at 48 w), suggesting a more important role of Brg1 than Arid1a in invasive IPMN. Here, ARID1A is linked to pancreatic intraductal papillary-mucinous neoplasm.