Applying GoNetic on the HMF cohort showed how the method successfully recovered both known PCa drivers (SPOP, FOXA1, and PTEN [40,41]) and known mPCa drivers (TP53, AR, RB1, APC, and CTNNB1 [1,12,14,37,38]). The gene discussed is APC; the disease is posterior cortical atrophy.