CD163 and acute myeloid leukemia: To understand what factors in AML may be important in contributing to alternative MΦ polarization and the induction of CD163 expression, we performed semi-quantitative cytokine array analyses using myeloblast CM from three AML patients with favorable, intermediate, or high genetic risk (patients #3, #18, and #23, respectively) and from two AML cell lines (HL-60 and U937; Figure 1E).