Similar results were obtained by Celli et al. [123], who showed clonal T-cell populations in different groups of patients with intestinal lymphocytosis (RCD-I, RCD-II, CeD and Helicobacter pylori-associated lymphocytosis); therefore, for appropriate diagnosis and classification of RCD, the results of TCR-γ gene rearrangement analyses should be interpreted cautiously, and immunophenotypic, histological and clinical data should also be considered. The gene discussed is TRGC1; the disease is cranioectodermal dysplasia.