Additionally, the anti-PD-1 mAbs-induced thyroiditis presented: (i) increased intrathyroidal CD4+PD-1+ T-lymphocytes (40.4% vs. 0.8%; p = 0.021) and CD8+PD-1+ T-lymphocytes (28.8% vs. 1.5%; p = 0.038) compared to the blood and (ii) increased circulating NK cells, CD4+CD8+ T-lymphocytes, CD4−CD8− γΔ (gamma-delta) T-lymphocytes, and intermediate monocytes. The gene discussed is CD4; the disease is thyroid gland disorder.