We performed a quantitative proteomics analysis according to the statistical design shown in Figure S3 for the individual IFNα responses for (1) normal astrocytes (Figure S4a); (2) two GBM cultures with a preserved antiviral response (Figure S4b,c); (3) two GBM cultures with a defective antiviral response (Figure S4d,e). Here, IFNA2 is linked to glioblastoma.