To reveal subtle differences in the ability of Type I IFNs to induce the antiviral state in eight GBM cultures obtained from individual patients, we pretreated cells with IFNα or IFNβ before infecting them with VSV-I and some other non-pathogenic viruses: NDV-H, PV3, Echo12, Coxsackie A7, and Coxsackie B5. This evidence concerns the gene IFNA2 and glioblastoma.