MKI67 and neoplasm: Histopathological criteria associated with poor survival are atypical mitosis [9,28,65,77], aneuploidy [9,65,147] (no effect [7,29]), tumor necrosis [7,8,9,29,65,77,78,94], high Ki67 expression [4,47,54,65,69,71,94,125] (no effect [45]), and high mitotic index [7,9,28,65,69,77,78,94,147] (no effect [29,59]).