Gap closure and transwell invasion assays were used to characterize the anti-metastatic effects of BPD-based PDP, Cet-BPD-based PDP, and EP4 inhibition, alone and in combination, in two high-grade serous ovarian adenocarcinoma lines (OVCAR-5, CAOV3). This evidence concerns the gene PDP1 and ovarian serous adenocarcinoma.