Likewise, groups treated with fluoxetine, wheatgrass, or their combination showed a significant increase in BDNF contents by 112.9, 73.4, and 138.8%, respectively, when compared to the AD group as shown in Figure 1D. However, groups treated with fluoxetine showed a significant decline in BDNF compared to groups that received wheatgrass. This evidence concerns the gene BDNF and Alzheimer disease.