In terms of the molecular mechanism of PT, previous reports have indicated that PT could inhibit tumor growth through the downregulation of Janus kinase/signal transducers 3 (JAK/STAT3), AKT/mTOR, and human telomerase reverse transcriptase (hTERT), and upregulation of the 5′-adenosine monophosphate activated protein kinase (AMPK), extracellular signal-regulated protein kinase 1/2 (ERK1/2), tumor protein P53 (p53), autophagy, nuclear factor erythroid 2-related factor 2 (Nrf2), and epigenetic regulated pathways [19,20,22,23,24,25]. Here, AKT1 is linked to neoplasm.