Based on the further experimental results, which confirmed ROS generation, as well as significantly increased total lysate protein with the phosphorylation (i.e., kinase induction) of FAK, AKT, p70S6K (ribosomal protein S6 kinase beta-1), and PAK1 after 6 h of erinacine treatment, it was concluded that erinacine exerts its inhibition on gastric cancer cell invasion and metastasis through ROS→p-FAK→p-AKT→p-p70mTOR→p-PAK→1433S/MTUS2 pathway [180]. Here, RPS6KB1 is linked to gastric cancer.