Swollen 28-joint count (SJC-28), Tender 28-joint count (TJC-28), CRP, erythrocyte sedimentation rate (ESR), uncarboxylated osteocalcin (UCOC), MMP-3, TNF, IL-6, and DAS28-ESR (Diseases Activities Score-28 for Rheumatoid Arthritis with ESR) levels are also decreased [44]. This evidence concerns the gene CRP and rheumatoid arthritis.