Here, we enclosed the LPAR6 expression was higher in brain and central nervous system (CNS) cancer, gastric, liver cancer, kidney, lymphoma and pancreatic cancer compared to the normal tissues and lower mRNA expression level of LPAR6 was observed in breast, bladder, colorectal, cervical, lung, esophageal, prostate cancer and some other types of cancer compared to the adjacent normal tissues (cancer vs. normal) (Figure 1A). This evidence concerns the gene LPAR6 and Familial prostate cancer.