The differential mRNA expression level of LPAR6 between tumor and matched normal and GTEx data across all TCGA tumors by GEPIA2 are demonstrated in Figure 1C. LPAR6 expression was significantly higher in glioblastoma multiforme (GBM), KIRC, LAML, lower grade glioma (LGG), PAAD, thymoma (THYM) and lower in adrenocortical carcinoma (ACC), ESCA, KICH, LUAD, PRAD, testicular germ cell tumors (TGCT), UCEC and UCS compared with normal GTEx tissues. This evidence concerns the gene LPAR6 and central nervous system cancer.