DNASE1 and melanoma: Using three murine tumor models, including melanoma B16, it was confirmed that the antimetastatic effect of DNase I correlated with the decrease in the levels of tandem repeats of SINE/LINE elements and some oncogenes in cfDNA [20]; thus, it was proposed that SINEs and LINEs, as well as fragments of oncogenes in the cfDNA, could be the targets of DNase I in the implementation of its antimetastatic effect.