Another attempt to use gene expression profiling in order to develop a prognostically relevant molecular classification of MM was made by Zhan et al. [32] The findings indicated the presence of seven disease subtypes that were strongly influenced by known genetic lesions including c-MAF– and MAFB-, CCND1- and CCND3-, MMSET-activating translocations and hyperdiploidy, these being CD1 [(t(11;14)], CD2 [t(11;14) and t(11;16)], MS [t(4;14)], MF [t(14;16) and t(14;20)], hyperdiploid cluster (HY), low bone disease (LB), and proliferation-associated genes (PR). Here, CCND3 is linked to Miyoshi myopathy.