ENPP2 and open-angle glaucoma: That is, Ho et al. reported that the ATX protein and LPA levels in AH from patients with primary open angle glaucoma (POAG) (ATX; 216.55 ± 15.37 ng/mL, LPA; 16:0; 11.3 ± 2.6 nM, 18:0; 3.4 ± 0.9 nM, 18:1; 10.2 ± 2.0 nM) were significantly increased as compared to patients with cataracts (ATX; 132.89 ± 6.67 ng/mL p < 0.001, LPA; 16:0; 1.3 ± 0.6 nM p < 0.001, 18:0; 3.5 ± 0.3 nM p = 0.825, 18:1; 3.5 ± 0.4 nM p = 0.003) [15].