EGFR and colorectal cancer: The use of an anti-EGFR antibody to detect human colorectal cancer-derived EGFR-expressing exosomes has been shown elsewhere [30]; Cavallaro et al. reported the use of an anti-EGFR Affibody-functionalized silica micro-capillary to promote the binding of small EGFR-positive EVs for an electro-kinetic-based detection approach [31].