DEGs down-regulated with HF were highly enriched for genes involved in biological processes: lipid metabolic process (GO:0006629; PFDR = 3.12 × 10−6), small molecule metabolic process (GO:0044281; PFDR = 3.12 × 10−5), and response to hormone (GO:0009725; PFDR = 8.44 × 10−3) including Acaca, Acly, Hnf4a, Ucp3 and Pck1 (Table S2) and coding for proteins localized in the mitochondrial envelope (GO:0005740; PFDR = 6.58 × 10−3). This evidence concerns the gene ACLY and hydrops fetalis.