NFKB1 and diabetic kidney disease: Noncoding RNA is also involved in the progression of DKD inflammation and fibrosis [163] (Table 1), and it is known that long noncoding RNAs (lncRNAs) participate in the initiation and progression of DKD by exerting direct pathogenic effects, or by indirectly mediating specific renal pathways (such as TGF-β1, NF-κB, STAT3, and GSK-3β signaling) [164].