FUS and amyotrophic lateral sclerosis: Many mutations leading to familial ALS cases have been described, the most common ones being mutations in SOD1, FUS (fused in sarcoma/translocated in liposarcoma or heterogenous nuclear ribonucleoprotein P2), C9orf72 (chromosome 9 open reading frame 72), and TARDP (transactive response DNA binding protein 43) [343,344], the study of which can help identify the pathophysiologic mechanisms of the disease.