RAB3D and synovial sarcoma: Vesicle associated molecular protein 8, Rab3D, aquaporin 5, β-fodrin, and angiotensin II type 2 receptor are translocated from apical membrane to cytoplasma or basal side of lacrimal gland epithelia, resulting in dysregulated production of tear component and loss of tear secretion leads to severe dry eye disease in Sjogren’s syndrome (SS).